I loved Harry Anderson's work, really enjoyed Night Court, and he was also a very entertaining stand up magician/comic. I don't think that show works with anyone else in that role, it set the right irreverent but responsible tone needed for that role.
It's zany, had a hard time getting on the air b/c it wasn't a typical sitcom and was really edgy in some ways for its time (esp. the Dan Fielding character).
Powerful show with Anderson and John Laroquette on that show.
He was quite young, only 65. He intentionally retired from big time "showbiz", and for a long time had a magic shop down in New Orleans, moved to Ashville some years ago.